Polycythemia Vera Market Analysis, Market Size, Epidemiology, Leading Companies, Drugs and Competitive Analysis by DelveInsight
Polycythemia Vera Market
DelveInsight
has launched a report on “Polycythemia Vera - Market
Insights, Epidemiology, and Market Forecast-2030”
DelveInsight's
"Polycythemia Vera -
Market Insights, Epidemiology, and Market Forecast-2030" report
delivers an in-depth understanding of the Polycythemia Vera , historical and
forecasted epidemiology as well as the Polycythemia Vera market trends in the United
States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.
Some of the Facts:
1.
According to DelveInsight, total prevalent
population of Polycythemia Vera (PV) in the 7MM was found to be 301,833 in
2017.
2.
Most of the diagnosed prevalence of PV was found
in the United States with 107,760 cases in 2017.
3.
Japan had 22,974 diagnosed prevalent cases for
PV in 2017.
4. Among
EU5, Germany had the highest diagnosed prevalent population of PV with 12,085
cases
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Key facts of the
report:
1. Polycythemia Vera market
report covers a descriptive overview and comprehensive insight of the Polycythemia Vera epidemiology and Polycythemia Vera market in the 7 MM (United
States, EU5 (Germany, Spain, France, Italy, UK) & Japan.)
2. Polycythemia Vera market
report provides insights on the current and emerging therapies.
3. Polycythemia Vera market
report offers a global historical and forecasted market covering drug outreach
in 7MM.
4. Polycythemia Vera market
report provides an edge that will help in developing business strategies by
understanding trends shaping and driving the Polycythemia Vera market.
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“As per DelveInsight’s analysis, the therapeutic market of
Polycythemia Vera (PV) in the seven major markets was assessed to be USD
1,099.54 million in 2017”
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Polycythemia Vera (PV) is a rare condition characterized by
the progressively increased number of red blood cells in bloodstream, white
blood cells (WBC) and platelets also increase in number in the affected people.
This condition is known as myeloproliferative neoplasms, where the body
produces too many of these cells (RBC, WBC and Platelets). These new cells
cause the blood to be thicker than usual, increasing the risk for blood clots
that can block blood flow in arteries and veins. If a blood clot occurs in the
veins, deep in the arms and the legs, it is known as deep vein thrombosis
(DVT).
Mutation in the JAK2 kinase is responsible for PV. Most
cases of PV are associated with genetic changes that are somatic, not in the
egg and sperm cells, which pass on genetic information to offspring.
The diagnosis of PV is done by testing the blood for levels
of a hormone called erythropoietin or testing the blood for mutations in JAK2.
Bone marrow aspiration and biopsy are also done to confirm whether or not a
person has PV. The diagnostic test also includes Complete blood count (CBC) to
measure the number and quality of WBCs, RBCs, and platelets.
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Some of the key
companies working on Polycythemia Vera are:
- AstraZeneca
- Array
Biopharma
- SpringWorks
Therapeutics
And Many Others.
The launch of the emerging therapies is expected to
significantly impact the Polycythemia Vera treatment scenario in the upcoming
years:-
Drugs Covered:
- Jakafi
(Ruxolitinib): Incyte Corporation/Novartis
- Besremi:
AOP Orphan Pharmaceuticals AG/ PharmaEssentia
- Idasanutlin:
Hoffmann-La Roche
- KRT-232:
Kartos Therapeutics
And Many Others002E
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Table of Contents:
1. Key Insights
2. Executive Summary
3. Polycythemia Vera
(PV) Market Overview at a Glance
3.1. Market (%)
Distribution of PV in 2017
3.2. Market (%)
Distribution of PV in 2030
4. Polycythemia Vera
(PV): Disease Background and Overview
4.1. Introduction
4.2. Polycythemia
Vera: A Type of MPN
4.3. Signs and Symptoms
of Polycythemia Vera
4.4. Causes of
Polycythemia Vera
4.5. Complications
due to Polycythemia Vera
4.6. Clinical
Aspects of Polycythemia Vera
4.7. Pathophysiology
of Polycythemia Vera
4.7.1. JAK2 V617F in
Polycythemia Vera
4.8. Diagnosis of Polycythemia
Vera
4.9. Diagnostic
Guidelines
4.9.1. British
Society for Hematology Guidelines for Polycythemia Vera (PV)
4.9.2. WHO
Diagnostic Guidelines
4.9.3. British
Society for Hematology Guideline
5. Case Reports
6. Epidemiology and
Patient Population
6.1. Methodology
6.2. Key Findings
6.3. Total Prevalent
Population of Polycythemia Vera in the 7MM
6.4. Total Diagnosed
Prevalent Population of Polycythemia Vera in the 7MM
6.5. Gender-Specific
Diagnosed Prevalence of Polycythemia Vera in the 7MM
6.6. Age-Specific
Diagnosed Prevalence of Polycythemia Vera in the 7MM
6.7. Diagnosed
Prevalence of Polycythemia Vera by Gene Mutation in the 7MM
7. United States
Epidemiology
7.1. Assumptions and
Rationale
7.2. KOL Insights
7.3. Total Prevalent
Population of Polycythemia Vera in the United States
7.4. Total Diagnosed
Prevalent Population of Polycythemia Vera in the United States
7.5. Gender-Specific
Diagnosed Prevalence of Polycythemia Vera in the United States
7.6. Age-Specific
Diagnosed Prevalence of Polycythemia Vera in the United States
7.7. Diagnosed
Prevalence of PV by Gene Mutation in the United States
8. EU5 Epidemiology
8.1. Germany
Epidemiology
8.1.1. Assumptions
and Rationale
8.1.2. Total
Prevalent Population of Polycythemia Vera in Germany
8.1.3. Total
Diagnosed Prevalent Population of Polycythemia Vera in Germany
8.1.4.
Gender-Specific Diagnosed Prevalence of Polycythemia Vera in Germany
8.1.5. Age-Specific
Diagnosed Prevalence of Polycythemia Vera in Germany
8.1.6. Diagnosed
Prevalence of PV by Gene Mutation in Germany
8.2. France
Epidemiology
8.2.1. Assumptions
and rationale
8.2.2. Total
Prevalent Population of Polycythemia Vera in France
8.2.3. Total
Diagnosed Prevalent Population of Polycythemia Vera in France
8.2.4.
Gender-Specific Diagnosed Prevalence of Polycythemia Vera in France
8.2.5. Age-Specific
Diagnosed Prevalence of Polycythemia Vera in France
8.2.6. Diagnosed
Prevalence of PV by Gene Mutation in France
8.3. Italy
Epidemiology
8.3.1. Assumptions
and Rationale
8.3.2. Total
Prevalent Population of Polycythemia Vera in Italy
8.3.3. Total
Diagnosed Prevalent Population of Polycythemia Vera in Italy
8.3.4.
Gender-Specific Diagnosed Prevalence of Polycythemia Vera in Italy
8.3.5. Age-Specific
Diagnosed Prevalence of Polycythemia Vera in Italy
8.3.6. Diagnosed
Prevalence of PV by Gene Mutation in Italy
8.4. Spain
Epidemiology
8.4.1. Assumptions
and Rationale
8.4.2. Total
Prevalent Population of Polycythemia Vera in Spain
8.4.3. Total
Diagnosed Prevalent Population of Polycythemia Vera in Spain
8.4.4.
Gender-Specific Diagnosed Prevalence of Polycythemia Vera in Spain
8.4.5. Age-Specific
Diagnosed Prevalence of Polycythemia Vera in Spain
8.4.6. Diagnosed
Prevalence of PV by Gene Mutation in Spain
8.5. United Kingdom
Epidemiology
8.5.1. Assumptions
and Rationale
8.5.2. Total
Prevalent Population of Polycythemia Vera in the United Kingdom
8.5.3. Total
Diagnosed Prevalent Population of Polycythemia Vera in the United Kingdom
8.5.4.
Gender-Specific Diagnosed Prevalence of Polycythemia Vera in the United Kingdom
8.5.5. Age-Specific
Diagnosed Prevalence of Polycythemia Vera in the United Kingdom
8.5.6. Diagnosed
Prevalence of PV by Gene Mutation in the United Kingdom
8.6. KOL Insights
9. Japan
Epidemiology
9.1. Assumptions and
Rationale
9.2. KOL Insights
9.3. Total Prevalent
Population of Polycythemia Vera in Japan
9.4. Total Diagnosed
Prevalent Population of Polycythemia Vera in Japan
9.5. Gender-Specific
Diagnosed Prevalence of Polycythemia Vera in Japan
9.6. Age-Specific
Diagnosed Prevalence of Polycythemia Vera in Japan
9.7. Diagnosed
Prevalence of PV by Gene Mutation in Japan
10. Treatment
Algorithm, Current Treatment, and Medical Practices
10.1. Treatment
Algorithm
10.2. Proposed
Guidelines for Polycythemia Vera
10.2.1. A British
Society for Haematology Guidelines for PV
10.2.2. National
Comprehensive Cancer Network (NCCN) Guidelines for Polycythemia Vera (PV)
10.2.3. European
Society for Medical Oncology Guidelines for Polycythemia Vera
11. Unmet Needs
12. Marketed
Products
12.1. Jakafi
(Ruxolitinib): Incyte Corporation/Novartis
12.1.1. Drug
Description
12.1.2. Regulatory
Milestones
12.1.3. Clinical
Development
12.1.4. Safety and
Efficacy
12.1.5. Product
Description
12.2. Besremi: AOP
Orphan Pharmaceuticals AG/ PharmaEssentia
12.2.1. Product
Description
12.2.2. Mechanism of
Action
12.2.3. Regulatory
Milestones
12.2.4. Advantages
and Disadvantages
12.2.5. Clinical
Development
12.2.6. Safety and
Efficacy
12.2.7. Product Profile
13. Emerging
Therapies
13.1. Key Cross
Competition
13.2. Idasanutlin:
Hoffmann-La Roche
13.2.1. Product
Description
13.2.2. Other
Developmental Activities
13.2.3. Advantages
and Disadvantages
13.2.4. Clinical
Development
13.2.5. Clinical
Trials Information
13.2.6. Safety and
Efficacy
13.2.7. Product
Profile
13.3. KRT-232:
Kartos Therapeutics
13.3.1. Product
Description
13.3.2. Clinical
Development
13.3.3. Clinical
Trials Information
13.3.4. Product
Profile
13.4. Givinostat:
Italfarmaco
13.4.1. Product
Description
13.4.2. Other
Developmental Activities
13.4.3. Advantages
and Disadvantages
13.4.4. Clinical
Development
13.4.5. Clinical
Trials Information
13.4.6. Safety and
Efficacy
13.4.7. Product
Profile
List to be continued
in the report………
14. Polycythemia
Vera (PV): 7MM Market Analysis
14.1. Key Findings
14.2. Market Size of
Polycythemia Vera in 7MM
14.3. Market Size of
Polycythemia Vera by Therapies in the 7MM
15. United States:
Market Outlook
15.1. United States
Market Size
15.1.1. Total Market
size of Polycythemia Vera in the United States
15.1.2. Market Size
of Polycythemia Vera by Therapies in the US
16. EU-5 countries:
Market Outlook
16.1. Germany Market
Size
16.1.1. Total Market
size of Polycythemia Vera in Germany
16.1.2. Market Size
of Polycythemia Vera by therapies in Germany
16.2. France Market
Size
16.2.1. Total Market
size of Polycythemia Vera in France
16.2.2. Market Size
of Polycythemia Vera by therapies in France
16.3. Italy Market
Size
16.3.1. Total Market
size of Polycythemia Vera in Italy
16.3.2. Market Size
of Polycythemia Vera by therapies in Italy
16.4. Spain Market
Size
16.4.1. Total Market
size of Polycythemia Vera in Spain
16.4.2. Market Size
of Polycythemia Vera by therapies in Spain
16.5. United Kingdom
Market Size
16.5.1. Total Market
size of Polycythemia Vera in the United Kingdom
16.5.2. Market Size
of Polycythemia Vera by therapies in the UK
17. Japan Market
Outlook
17.1. Japan Market
Size
17.1.1. Total Market
size of Polycythemia Vera in Japan
17.1.2. Market Size of
Polycythemia Vera by therapies in Japan
18. Market Drivers
19. Appendix
19.1. Report
Methodology
20. DelveInsight
Capabilities
21. Disclaimer
22. About
DelveInsight
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