Triple Negative Breast cancer (TNBC) Market Size, Epidemiology, Leading Companies, Drugs and Competitive Analysis by DelveInsight
(Albany, US) DelveInsight has launched a new report on “Triple Negative Breast Cancer (TNBC) Market Insights, Epidemiology, and Market Forecast-2030“
DelveInsight’s “Triple Negative Breast Cancer (TNBC)
Market Insights, Epidemiology, and Market Forecast-2030“ report
delivers an in-depth understanding of the Triple Negative Breast Cancer (TNBC),
historical and forecasted epidemiology as well as the Triple Negative Breast
Cancer (TNBC) market trends in the United States, EU5 (Germany, Spain, Italy, France,
and United Kingdom) and Japan.
Some of the Triple
Negative Breast facts:
- Market
Size of TNBC in the 7MM was found to be 438 Million in 2017.
- As
per breastcancer.org, about 70% of breast cancers diagnosed in people with
an inherited BRCA mutation, particularly BRCA1, are triple-negative.
- As
per several secondary sources, it can be concluded that TNBCs are
significantly larger and of higher grade, but less likely to have lymph
node metastases than non-TNBCs.
- Total
Diagnosed Incident cases of Triple Negative Breast Cancer in the 7MM
countries was 99,380 in 2017.
- DelveInsight
has also estimated the Sub-type specific cases of TNBC, which are ER-, PR-
and HER2- .
- In
the United States, there were 4,793 cases of HER2-TNBC, followed by PR-
and ER- sub-types.
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Scope of the Triple
Negative Breast Report:
- The
report covers the descriptive overview of Triple Negative Breast Cancer
(TNBC), explaining its causes, signs and symptoms, pathophysiology,
diagnosis and currently available therapies
- Comprehensive
insight has been provided into the Triple Negative Breast Cancer (TNBC)
epidemiology and treatment in the 7MM
- Additionally,
an all-inclusive account of both the current and emerging therapies for
Triple Negative Breast Cancer (TNBC) are provided, along with the
assessment of new therapies, which will have an impact on the current
treatment landscape
- A
detailed review of Triple
Negative Breast Cancer market; historical and forecasted is included
in the report, covering drug outreach in the 7MM
- The
report provides an edge while developing business strategies, by
understanding trends shaping and driving the global Triple Negative Breast
Cancer (TNBC) market
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Triple
Negative Breast Cancer is defined as the heterogeneous
breast cancer phenotype where the estrogen and progesterone receptor are
negative, as assessed by immunohistochemistry (IHC), and there is a lack of
overexpression of HER2, as assessed by immunohistochemistry (IHC), or the absence
of its gene amplification, as assessed by fluorescence in situ hybridization
technique. The epidemiological risk factor profiles also vary between TNBC
(ER-PR-HER2-) and other breast cancers.
TNBCs are frequently identified as hyper dense masses without
associated calcifications. The majority of TNBCs are histologically classified
as high-grade, invasive, ductal carcinomas of no special type with basal-like
features. Central necrosis, pushing tumor borders, a conspicuous lymphocytic
infiltrate, and fibrosis are common histologic features.
TNBC is
characterized by various aggressive clinical pathologic features including
onset at a younger age, higher mean tumor size, higher-grade tumors, and a
higher rate of node positivity. Overall, TNBCs show an aggressive phenotype
with a shorter time to relapse and metastatic disease than the more common hormone-receptorepositive
invasive ductal carcinomas.
TNBC frequently metastasizes to the viscera, liver, lung or
brain. However, this is not always the case as it may also have an
oligometastatic phenotype closer to ER+ BC, with only lymph node and bone
disease. TNBC is also heterogeneous in terms of time of recurrence. TNBC has a
higher rate of recurrence in the first 5 years and a lower rate of recurrence
afterwards. The pattern of late recurrence is generally associated with less
aggressive disease, frequently with bone metastases.
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Some of the TNBC
Companies:
- Merck
- Hoffmann-La
Roche
- Infinity
Pharmaceuticals
- CytoDyn
- Treadwell
Therapeutics
- And
Many Others
Triple
Negative Breast Cancer Drugs Covered:
- Pembrolizumab
- Ipatasertib
- IPI-549
- Leronlimab
(PRO 140)
- CFI-400945
- And
Many Others
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Table of Contents:
- Key
Insights
- Executive
Summary of Triple Negative Breast Cancer (TNBC)
- Competitive
Intelligence Analysis for Triple Negative Breast Cancer (TNBC)
- Triple
Negative Breast Cancer (TNBC): Market Overview at a Glance
- Triple
Negative Breast Cancer (TNBC): Disease Background and Overview
- Patient
Journey
- Triple
Negative Breast Cancer (TNBC) Epidemiology and Patient Population
- Treatment
Algorithm, Current Treatment, and Medical Practices
- Unmet
Needs
- Key
Endpoints of Triple Negative Breast Cancer (TNBC) Treatment
- Marketed
Products
- Emerging
Therapies
- Triple
Negative Breast Cancer (TNBC): Seven Major Market Analysis
- Attribute
analysis
- 7MM:
Market Outlook
- Access
and Reimbursement Overview of Triple Negative Breast Cancer (TNBC)
- KOL
Views
- Market
Drivers
- Market
Barriers
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About DelveInsight
DelveInsight is a leading Life Science market research and
business consulting company recognised for its off-the-shelf syndicated market
research reports as well as customised solutions to firms in the healthcare
sector.
Media Contact
Company Name: DelveInsight Business Research LLP
Contact Person: Ankit Nigam
Email: info@delveinsight.com
City: Albany
State: New York
Country: United States
Website: https://www.delveinsight.com/
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