What is Achondroplasia Treatment Market?
Achondroplasia is the most common of skeletal dysplasia that results in marked short stature (dwarfism). It is a human bone genetic disorder of the growth plate and is the most common form of inherited disproportionate short stature.
DelveInsight's "Achondroplasia
Market Insights, Epidemiology, and Market Forecast-2030" report
delivers an in-depth understanding of the Achondroplasia, historical and
forecasted epidemiology as well as the Achondroplasia market trends in the
United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and
Japan.
Some facts of Achondroplasia
Market Report
are:
·
According to Columbia University Medical Center
(CUMC), this disorder occurs in approximately 1 in 25,000 live births
worldwide.
·
The prevelance rates have correlation to
father’s age as mutations occur exclusively in the male and older men who have
a higher probability of having an affected child than younger ones (Deepali
N.shinde et al)
·
The population-based study conducted by
DK.Waller et al in US, stated that the prevalence of de novo Achondroplasia has
been significantly increased with age of father. The prevelance data varied
according to father’s age such as 25–29, 30–34, 35–39, and ≥40 years, with
reported rates of 2.8, 2.8, 4.9 and 5.0 respectively.
·
The prevalence of achondroplasia ranged from
0.36 to 0.60 per 10,000 livebirths
·
According to a study, the recurrence risk of
Achondroplasia among siblings of an affected individual was found to be 0.23%
(Mettler and Fraser)
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Scope of the Achondroplasia
Market Report
- The
report covers the descriptive overview of Achondroplasia, explaining its
causes, signs and symptoms, pathophysiology, diagnosis and currently
available therapies
- Comprehensive
insight has been provided into the Achondroplasia epidemiology and
treatment in the 7MM
- Additionally,
an all-inclusive account of both the current and emerging therapies for
Achondroplasia are provided, along with the assessment of new therapies,
which will have an impact on the current treatment landscape
- A
detailed review of Achondroplasia market; historical and forecasted is
included in the report, covering drug outreach in the 7MM
- The
report provides an edge while developing business strategies, by
understanding trends shaping and driving the global Achondroplasia market
List of Achondroplasia
Key Players involved in the report
- BioMarin
- Ascendis
Pharma
- Therachon
- Pfizer
- And
many others
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The children affected by Achondroplasia are delayed in
reaching gross motor milestones such as head control, and independent sitting
and walking. There are some serious neurological problems that may also occur
due to narrowing of the spinal canal and nerve compression.
Achondroplasia
Market Insights
It is caused by one of two mutations (G1138A and G1138C) in
the FGFR3 (Fibroblast Growth Factor Receptor 3) gene at chromosome locus
4p16.3. The mutations cause the FGFR3 protein to be overly active, which
interferes with skeletal development and leads to disturbances in bone growth
seen with this disorder.
·
Vosoritide
·
TA-46
·
TransCon CNP
·
Infigratinib (Bridgebio/Qued)
·
And Many others
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Achondroplasia Treatment Market
The current market is occupied with this symptomatic
treatment and surgery only. To be effective, a new treatment approach must
consider Achondroplasia is a complex disease, correcting the short stature and
preventing complications. Understanding the pathophysiology of the disease is
essential to achieve this and correcting the growth of all bones affected by
the disease, will define the future treatment strategy.
Table of Content:
1. Key Insights
2. Executive Summary
of Achondroplasia
3. Competitive
Intelligence Analysis for Achondroplasia
4. Achondroplasia:
Market Overview at a Glance
4.1. Achondroplasia Total Market Share (%) Distribution in
2018
4.2. Achondroplasia Total Market Share (%) Distribution in
2030
5. Achondroplasia:
Disease Background and Overview
6. Patient Journey
7. Achondroplasia
Epidemiology and Patient Population
8. Treatment
Algorithm, Current Treatment, and Medical Practices
9. Unmet Needs
10. Key Endpoints of
Achondroplasia Treatment
11. Marketed
Products
List to be continued in report
12. Emerging
Therapies
List to be continued in report
13. Achondroplasia:
Seven Major Market Analysis
14. Attribute
analysis
15. 7MM: Market
Outlook
16. Access and
Reimbursement Overview of Achondroplasia
17. KOL Views
18. Market Drivers
19. Market Barriers
20. Appendix
21. DelveInsight
Capabilities
22. Disclaimer
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·
Acute
Agitation And Aggression Market
·
Diagnostic
Imaging Equipment Market
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