Hereditary Angioedema Market Research Report 2032
DelveInsight’s “Hereditary Angioedema Market Insights, Epidemiology, and Market Forecast 2030” report delivers an in-depth understanding of the Hereditary Angioedema, historical and forecasted epidemiology as well as the Hereditary Angioedema market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.
Hereditary
Angioedema (HAE) is a rare genetic disorder caused by the
deficiency in functional C1 inhibitor (C1INH) that results in recurrent attacks
of localized subcutaneous or mucosal edema, most commonly affecting the skin,
intestines, upper respiratory tract, and oropharynx
HAE is a heterogeneous disease with complex pathophysiology
that involves several pathways resulting in the increased production of
bradykinin with mutations of multiple molecules in genetic etiology. These
could include the Kallikrein gene mutations; Bradykinin gene or its receptor
mutations; Kininase 1 gene mutations and loss of function and mutations in gene
encoding aminopeptidase and ACE enzymes.
It is classified into three types based on genetic defects
such as type I HAE with low levels of C1-INH in the body, type II with poorly
functioning C1-INH, or the recently identified types of HAE with normal
functioning C1-INH (formerly known as type III HAE). Identification of the novel
polymorphisms in several genes leading to modification in the clinical
phenotype of HAE is a relatively recent phenomenon. The clinical features of
HAE are recurrent and unpredictable spontaneous edema attacks. Traumas,
infections, stress, or medical procedures are potential triggers for HAE
attacks, and occasionally, angioedema could be associated with prodromal signs,
including erythema marginatum.
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The Hereditary
Angioedema market report also covers emerging drugs, current
treatment practices, Hereditary Angioedema market share of the individual
therapies, current and forecasted Hereditary Angioedema Market Size from 2019
to 2032 segmented by seven major markets.
The report provides a detailed current Hereditary Angioedema
treatment practice/algorithm, market drivers, market barriers and unmet medical
needs to curate best of the opportunities and assesses the underlying potential
of the market.
Hereditary
Angioedema Market Key Facts
·
Total diagnosed prevalent population of
Hereditary Angioedema (HAE) in 7MM countries was estimated to be
14,435 cases in 2017.
·
Among the European countries, France had the
highest prevalent population of 1,346 cases, followed by the UK which had
prevalent population of 1,301 in 2017.
·
HAE in the US has been observed with the maximum
number of diagnosed cases in the age-group 17 to below 65 years, followed by
those who belong to the age-group 12 to less than 17 years.
·
Among the European 5 countries, Spain had the
lowest prevalent population with 537 cases in 2017.
Key Benefits of Hereditary
Angioedema Market Report
- Hereditary
Angioedema market report provides an in-depth analysis of
Hereditary Angioedema Market Size, Share, Trend, Epidemiology and Market
Forecast till 2030, in 7 major market i.e. EU5 (Germany, Italy, Spain,
France and the UK), Japan, and the United States.
- The
Hereditary Angioedema market report will help in developing business
strategies by understanding the Hereditary Angioedema Market
trends & developments, key players and future market competition
that will shape and drive the Hereditary Angioedema market in the upcoming
years.
- The Hereditary
Angioedema market report covers Hereditary Angioedema current
treatment practices, emerging drugs, market share of the individual
therapies in 7 MM.
- The
report provides a detailed assessment of the Hereditary Angioedema
market in terms of market drivers & barriers, Unmet Needs,
market opportunities, patient population, comparative analysis of
pipeline products with detailed clinical profiles, and other
factors.
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The landscape of therapeutic options for patients with HAE
has changed dramatically in the last two decades. Ongoing research promises
even greater change in the foreseeable future. Given the economic and
psychosocial burdens for patients living with angioedema, effective therapies
with novel mechanisms will offer more choices for patients and physicians, as
well as provide greater flexibility in routes of administration. Owing
to the launch of upcoming therapies, market size shall increase during forecast
period (2017-2030).
The Hereditary
Angioedema market outlook section
of the report helps to build the detailed comprehension of the historic,
current and forecasted Hereditary Angioedema market trends by analyzing the
impact of current therapies on the market, unmet needs, drivers and barriers
and demand for better technology.
The report gives a thorough detail of Hereditary
Angioedema market trend of each marketed drug and late-stage pipeline
therapy by evaluating their impact based on the annual cost of therapy,
inclusion and exclusion criteria, mechanism of action, increasing patient pool,
covered patient segment, expected launch year, competition with other
therapies, and view of the key opinion leaders.
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Hereditary
Angioedema Epidemiology
The Hereditary Angioedema epidemiology section
covers insights about historical and current Hereditary Angioedema patient pool
and forecasted trends for every seven major countries (i.e. the United States,
EU5 countries (Germany, Spain, Italy, France, and the United Kingdom), and
Japan from 2017 to 2030.
It helps to recognize the causes of current and forecasted
trends by exploring numerous studies and views of key opinion leaders. The
epidemiology section also provides the diagnosed patient pool and their trends
along with assumptions undertaken.
Hereditary
Angioedema Drugs Uptake and Key Market Players
The Hereditary Angioedema Drugs Uptake section
focuses on the rate of uptake of the potential drugs recently launched in the
Hereditary Angioedema market or expected to get launched in the market during
the study period. The analysis covers Hereditary Angioedema market uptake by
drugs; patient uptake by therapies; and sales of each
drug.
Report’s Drugs Uptake section helps in understanding the
drugs with the most rapid uptake, reasons behind the maximal use of new drugs
and allow the comparison of the drugs on the basis of market share and size
which again will be useful in investigating factors important in market uptake
and in making financial and regulatory decisions.
Companies are focusing on executing a successful launch that
meets the urgent demand for a once-daily oral therapy that will allow HAE
patients to live a more normal life. An orally delivered, small molecule offers
the opportunity to improve treatment for the disease by making it more
convenient for patients to take therapies
Some of the key players in the Hereditary
Angioedema Market includes:
·
BioCryst Pharmaceuticals
·
Ionis Pharmaceuticals
·
KalVista Pharmaceuticals
·
CSL Behring
·
Takeda
·
Shire
·
Pharming Group
·
And many others.
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Hereditary
Angioedema Drugs Covered
·
BCX7353
·
IONIS-PKK-LRx
·
KVD900
·
CSL312
·
And many others.
Table of Content
1. Key Insights
2. Executive Summary
3. Hereditary Angioedema Competitive Intelligence Analysis
4. Hereditary Angioedema Market Overview at a Glance
5. Hereditary Angioedema Disease Background and Overview
6. Hereditary Angioedema Patient Journey
7. Hereditary Angioedema Epidemiology and Patient Population
8. Hereditary Angioedema Treatment Algorithm, Current
Treatment, and Medical Practices
9. Hereditary Angioedema Unmet Needs
10. Key Endpoints of Hereditary Angioedema Treatment
11. Hereditary Angioedema Marketed Products
12. Hereditary Angioedema Emerging Therapies
13. Hereditary Angioedema Seven Major Market Analysis
14. Attribute Analysis
15. Hereditary Angioedema Market Outlook (7 major markets)
16. Hereditary Angioedema Access and Reimbursement Overview
17. KOL Views on the Hereditary Angioedema Market.
18. Hereditary Angioedema Market Drivers
19. Hereditary Angioedema Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
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