Alopecia Areata Treatment Market Size, Epidemiology, Drugs Pipeline, Market Analysis and Companies by DelveInsight
Alopecia Areata (AA), an autoimmune skin disorder, in which the hair follicles get damaged by a faulty immune system. This faultiness causes the immune system to attack its own body, thus disrupting hair follicles and new hair formation. Biopsies performed have clearly shown the immune lymphocytes travelling in the hair bulbs of the hair follicle. The condition can lead to extreme hair loss in aggravated stages from the entire body, known as Alopecia universalis or it can lead to overall loss of hair from the scalp area, also called Alopecia Totalis.
DelveInsight's "Alopecia
Areata Market Insights, Epidemiology, and Market Forecast-2030" report
delivers an in-depth understanding of the Alopecia Areata, historical and
forecasted epidemiology as well as the Alopecia Areata market trends in the
United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and
Japan.
·
Patchy hair loss
·
Inflammation of the hair follicles
·
Cadaver hairs
·
White spots and lines appear
·
Pinpoint dents appear
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Some facts of Alopecia Areata Market Report:
·
According to the Chantal Bolduc et al., 2018,
the prevalence of alopecia areata (AA) in the general population is estimated
to be 0.1–0.2%. The lifetime risk of developing alopecia areata is estimated to
be 1.7%. All races are affected equally by alopecia areata and no increase in
prevalence has been found in a particular ethnic group.
·
As per the study conducted by Alexandra C.
Villasante Fricke et al. in 2015, the scalp is the most common site of
involvement, with or without involvement of other body sites (such as the
eyebrows, eyelashes, and beard). Specifically, the most common site was the
occipital region, involved in 38.4% of males and 33.4% of females. Upon first
presentation, 58% of adult patients had patchy hair loss with less than half
the scalp involved. On the other hand, in children, 80–85% had mild-to-moderate
hair loss involving less than half the scalp.
·
As per the National Organization of Rare
Disease, alopecia areata is most common among the children and approximately
2.5 million people are suffering from alopecia areata in the United States.
·
As per Herbert Pratt et al. 2017, alopecia
areata affects approximately two percent of the general population at some
point during their lifetime
·
According to the National Alopecia Areata
Foundation, approximately 6.8 million people in the United States and 147 million
worldwide have or will develop alopecia areata at some point in their lives.
·
As per Alexandra C Villasante Fricke et al.,
2015, patients with AA experience their first onset of AA by age 40 years in
82.6–88% of patients and by age 20 years in 40.2% of patients. The mean age of
onset has been reported as between 25.2 and 36.3 years. In children, the mean
age of onset has been reported as between ages 5 and 10 years.
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Alopecia Areata Treatment Market
The treatments commonly prescribed to AA patients include
Injections, Oral, Topical Treatments and Light therapy.
Alopecia Areata Injections:
Steroid injections are commonly used in the treatment of AA,
mainly for bald and patchy areas on the scalp. Steroidal injections are
injected on the bare part of the affected area. Although it does not stop the
hair fall, but effectively helps in regeneration of hair. The treatment is to
be repeated in every one to two months.
Alopecia Areata Oral
Treatments:
Cortisone tablets are majorly recommended for severe forms
of AA. However, cortisone causes major side effects as well. Immunosuppressants
such as methotrexate and cyclosporine are also recommended. They work by
creating an obstruction for the immune system, but they cannot be ingested for
prolonged periods due to serious side effects such as lymphoma, kidney and
liver damages etc.
Alopecia Areata Topical
Treatments:
Many types of topical treatments are rubbed on the scalp
area and other regions of the body including eyebrows and beard. These involve
Minoxidil (Rogaine), Anthralin (Dritho-Scalp), clobetasol (Impoyz),
Diphencyprone etc.
Alopecia Areata Light
Therapy:
This form of therapy uses a combination of psoralens and
Ultra-violet light to treat AA.
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Some of Alopecia Areata Companies are:
·
Pfizer
·
Suzhou Zelgen Biopharmaceuticals
·
Eli Lilly and Company
·
Incyte Corporation
·
Aclaris Therapeutics
·
Legacy Healthcare
·
Concert Pharmaceuticals
·
LEO
Pharma
·
Bristol-Myers Squibb
·
And Many Others
Alopecia Areata Therapies are:
·
PF-06651600
·
Jaktinib
·
Baricitinib
·
ATI-502
·
Abatacept
·
LH-8
·
LEO 124249
·
CTP-543
·
And Many Others
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Table of Contents:
1. Key Insights
2. Executive Summary
of Alopecia Areata
3. Competitive
Intelligence Analysis for Alopecia Areata
4. Alopecia Areata:
Market Overview at a Glance
4.1. Alopecia Areata Total Market Share (%) Distribution in
2018
4.2. Alopecia Areata Total Market Share (%) Distribution in
2030
5. Alopecia Areata:
Disease Background and Overview
6. Patient Journey
7. Alopecia Areata
Epidemiology and Patient Population
8. Treatment
Algorithm, Current Treatment, and Medical Practices
9. Unmet Needs
10. Key Endpoints of
Alopecia Areata Treatment
11. Marketed
Products
List to be continued in report
12. Emerging
Therapies
List to be continued in report
13. Alopecia Areata:
Seven Major Market Analysis
14. Attribute
analysis
15. 7MM: Market
Outlook
16. Access and
Reimbursement Overview of Alopecia Areata
17. KOL Views
18. Market Drivers
19. Market Barriers
20. Appendix
21. DelveInsight
Capabilities
22. Disclaimer
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