Anaphylaxis Market Size, Epidemiology Facts, Key Players, Therapies, and Market Report 2032
Anaphylaxis is an acute, potentially life-threatening, generalized, or systemic allergic reaction that is mediated by the degranulation of mast cells and basophils. The condition usually develops suddenly and gets worse very quickly.
DelveInsight's "Anaphylaxis
Market Insights, Epidemiology, and Market Forecast-2032" report
delivers an in-depth understanding of the Anaphylaxis, historical and
forecasted epidemiology as well as the Anaphylaxis market trends in the United
States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.
The Anaphylaxis Market report provides an
edge while developing business strategies, by understanding trends shaping and
driving the global Anaphylaxis market. A detailed review of the historical and
forecasted Anaphylaxis market is included in the report, covering drug outreach
in the 7MM.
Some of the key highlights of the Anaphylaxis
Market Report
- A
study titled “The Epidemiology of Anaphylaxis”, wherein the lifetime
prevalence of anaphylaxis was estimated at 0.05–2% in the USA and
approximately 3% in Europe. The study also mentioned that in UK, of
patients presenting to paramedics and first aides estimated 0.2% of
emergency cases due to anaphylaxis.
- Biphasic
anaphylaxis is a recurrence of anaphylaxis after appropriate treatment. It
happens with no additional exposure to the allergen and strikes after the
patient has survived the initial attack.
- Anaphylaxis
develops rapidly, usually reaching peak severity within 5 to 30 minutes,
and may, rarely, last for several days.
- Approximately
1 in 5 admissions to hospitals in England due to allergies were for an
anaphylactic reaction (4070 out of 20,318). This was an increase of 9.9%
on the same period in the previous year. The NICE CG134 guideline reported
an available UK estimate that about 1 in 1,333 of the population of
England had experienced anaphylaxis at some point in their lives. However,
a systematic review published in 2013 estimated that 1 in 300 people in
Europe were affected by anaphylaxis at some point in their lives
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Anaphylaxis Epidemiology Insights
The lifetime prevalence of anaphylaxis has been estimated at
1.6% to 5.1%. Medications and stinging insects are the leading triggers in
adults, with foods and stinging insects the most frequently implicated triggers
in children and adolescents. Food allergy impacts 8% to 11% of children and
adults in the United States, while adverse drug reactions (ADRs) affect up to
10% of the population (and 20% of hospitalized patients), with hypersensitivity
reactions (HSRs) accounting for 10% of all ADRs.
Anaphylaxis Epidemiology Segmentation in the 7MM
(2019-2032)
- Anaphylaxis
Prevalent Population
- Anaphylaxis
Diagnosed and Treatable Cases
- Anaphylaxis
Trigger-specific Population
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Anaphylaxis is variable and unpredictable. It may be mild
and resolve spontaneously due to endogenous production of compensatory
mediators or it may be severe and progress within minutes to respiratory or
cardiovascular compromise and death. The treatment for anaphylaxis majorly
includes the use of epinephrine to prevent the possible progression to
life-threatening manifestations. When the patient is admitted at the hospital,
they might receive glucocorticoid and antihistamines intravenously. These
medications help to reduce inflammation in the air passages, improving your
ability to breathe. They may also be given beta-agonists such as albuterol to
make breathing easier and may also receive supplemental oxygen to help the body
get the oxygen it needs.
Anaphylaxis Symptoms
The symptoms include feeling lightheaded or faint, breathing
difficulties – such as fast, shallow breathing, wheezing, fast heartbeat,
clammy skin, confusion and anxiety, collapsing or losing consciousness. There
may also be other allergy symptoms, including an itchy, raised rash (hives),
feeling or being sick, swelling (angioedema) or stomach pain.
Anaphylaxis Diagnosis
A blood test to measure the amount of a certain enzyme
(tryptase) that can be elevated up to three hours after anaphylaxis is
analyzed. In addition, the patient is tested for allergies with skin tests or
blood tests to help determine the trigger. The differential diagnosis for
anaphylaxis includes respiratory difficulty or circulatory collapse, including
vasovagal reactions, globus hystericus, status asthmaticus, foreign body aspiration,
pulmonary embolism, epiglottitis, myocardial infarction, carcinoid syndrome,
hereditary angioedema, pheochromocytoma and other. Upper airway obstruction,
bronchospasm, abdominal cramps, pruritus, urticaria and angioedema are absent
in vasovagal reactions. Pallor, syncope, diaphoresis and nausea usually
indicate a vaso-vagal reaction but may occur in either condition.
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Anaphylaxis Companies
- Pfizer
- Adamis
Pharmaceuticals
- Aquestive
Therapeutics
- Wyss
Institute, and others
Anaphylaxis Drugs
- AbbieSense
technology
- AQST-109
- AQST-108
- Symjepi
- EpiPen
and EpiPen Jr, and others
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Anaphylaxis Emerging Therapy Assessment
The pipeline of Anaphylaxis possess potential key player,
such as Aquestive Therapeutics, Wyss Institute and others. The dynamics of
Anaphylaxis market is anticipated to change in the coming years owing to the
improvement in the research and development activities so that market will
comprise of efficient treatment options. The launch of emerging therapies is
expected during the forecast period of 2021–2030.
Table of content
1. Key Insights
2. Executive Summary
3. Competitive Intelligence Analysis
4. Market Overview at a Glance
5. Disease Background and Overview
6. Patient Journey
7. Anaphylaxis Epidemiology and Patient Population
8. Treatment Algorithm, Current Treatment, and Medical
Practices
9. Unmet Needs
10. Key Endpoints of Anaphylaxis Treatment
11. Marketed Products
12. Emerging Therapies
13. Seven Major Market Analysis
14. Attribute analysis
15. 7MM: Market Outlook
16. Access and Reimbursement Overview
17. KOL Views
18. Market Drivers
19. Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
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About DelveInsight
DelveInsight is a leading Business Consultant, and Market
Research Firm focused exclusively on life sciences. It supports pharma
companies by providing end-to-end comprehensive solutions to improve their
performance.
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